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 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
30/06/2023 |
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Actualizado : |
30/06/2023 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
GIANNITTI, F.; GARCÍA, J. P.; ADAMS, V.; ARMENDANO, J.; BEINGESSER, J.; ROOD, J.; UZAL, F. A. |
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Afiliación : |
FEDERICO GIANNITTI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; JORGE P. GARCÍA, Universidad Nacional del Centro de la Provincia de Buenos Aires, Tandil, Buenos Aires, Argentina; VICKI ADAMS, Monash University, Parkville, Victoria, Australia; JOAQUÍN I. ARMENDANO, Universidad Nacional del Centro de la Provincia de Buenos Aires, Tandil, Buenos Aires, Argentina; JULIANN BEINGESSER, California Animal Health and Food Safety Laboratoy, University of California at Davis, San Bernardino, CA; JULIAN I. ROOD, Monash University, Parkville, Victoria, Australia; FRANCISCO A. UZAL, Monash University, Parkville, Victoria, Australia. |
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Título : |
Experimental acute Clostridium perfringens type D enterotoxemia in sheep is not characterized by specific renal lesions. |
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Complemento del título : |
Infectious Disease - Original Article. |
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Fecha de publicación : |
2023 |
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Fuente / Imprenta : |
Veterinary Pathology. 2023, vol.60(4):412-419. https://doi.org/10.1177/03009858231171669 |
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ISSN : |
0300-9858 (print); 1544-2217 (online). |
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DOI : |
10.1177/03009858231171669 |
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Idioma : |
Inglés |
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Notas : |
Article history: First published online May 12, 2023. -- Corresponding Author: Francisco A. Uzal, California Animal Health and Food Safety Laboratory, School of Veterinary Medicine, University of California at Davis, 105 W CVentral Ave, San Bernardino, CA 92408, USA. Email: fauzal@ucdavis.edu -- Funding: This work was supported by grant R01 AI056177 from the National Institute of Allergy and Infectious Diseases (NIAID). Research at Monash University was also supported by funding provided by the Australian Research Council to the Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics (grant no. CE0562063). -- |
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Contenido : |
ABSTRACT.- Type D enterotoxemia, caused by Clostridium perfringens epsilon toxin (ETX), is one of the most economically important clostridial diseases of sheep. Acute type D enterotoxemia is characterized by well-documented lesions in the nervous, cardiocirculatory, and pulmonary systems. However, discrepancies and confusion exist as to whether renal lesions are part of the spectrum of lesions of this condition, which is controversial considering that for many decades it has been colloquially referred to as "pulpy kidney disease". Here, the authors assess renal changes in an experimental model of acute type D enterotoxemia in sheep and evaluate the possible role of ETX in their genesis. Four groups of 6 sheep each were intraduodenally inoculated with either a wild-type virulent C. perfringens type D strain, an etx knockout mutant unable to produce ETX, the etx mutant strain complemented with the wild-type etx gene that regains the ETX toxin production, or sterile culture medium (control group). All sheep were autopsied less than 24 hours after inoculation; none of them developed gross lesions in the kidneys. Ten predefined histologic renal changes were scored in each sheep. The proportion of sheep with microscopic changes and their severity scores did not differ significantly between groups. Mild intratubular medullary hemorrhage was observed in only 2 of the 12 sheep inoculated with the wild-type or etx-complemented bacterial strains, but not in the 12 sheep of the other 2 groups. The authors conclude that no specific gross or histologic renal lesions are observed in sheep with experimental acute type D enterotoxemia. © The Author(s) 2023 MenosABSTRACT.- Type D enterotoxemia, caused by Clostridium perfringens epsilon toxin (ETX), is one of the most economically important clostridial diseases of sheep. Acute type D enterotoxemia is characterized by well-documented lesions in the nervous, cardiocirculatory, and pulmonary systems. However, discrepancies and confusion exist as to whether renal lesions are part of the spectrum of lesions of this condition, which is controversial considering that for many decades it has been colloquially referred to as "pulpy kidney disease". Here, the authors assess renal changes in an experimental model of acute type D enterotoxemia in sheep and evaluate the possible role of ETX in their genesis. Four groups of 6 sheep each were intraduodenally inoculated with either a wild-type virulent C. perfringens type D strain, an etx knockout mutant unable to produce ETX, the etx mutant strain complemented with the wild-type etx gene that regains the ETX toxin production, or sterile culture medium (control group). All sheep were autopsied less than 24 hours after inoculation; none of them developed gross lesions in the kidneys. Ten predefined histologic renal changes were scored in each sheep. The proportion of sheep with microscopic changes and their severity scores did not differ significantly between groups. Mild intratubular medullary hemorrhage was observed in only 2 of the 12 sheep inoculated with the wild-type or etx-complemented bacterial strains, but not in the 12 sheep of the other 2 ... Presentar Todo |
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Palabras claves : |
Clostridium perfringens type D; Enterotoxemia; ETX; Experimental infection; Kidneys; PLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA; Renal pathology; Sheep. |
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Asunto categoría : |
L10 Genética y mejoramiento animal |
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Marc : |
LEADER 03352naa a2200325 a 4500
001 1064216
005 2023-06-30
008 2023 bl uuuu u00u1 u #d
022 $a0300-9858 (print); 1544-2217 (online).
024 7 $a10.1177/03009858231171669$2DOI
100 1 $aGIANNITTI, F.
245 $aExperimental acute Clostridium perfringens type D enterotoxemia in sheep is not characterized by specific renal lesions.$h[electronic resource]
260 $c2023
500 $aArticle history: First published online May 12, 2023. -- Corresponding Author: Francisco A. Uzal, California Animal Health and Food Safety Laboratory, School of Veterinary Medicine, University of California at Davis, 105 W CVentral Ave, San Bernardino, CA 92408, USA. Email: fauzal@ucdavis.edu -- Funding: This work was supported by grant R01 AI056177 from the National Institute of Allergy and Infectious Diseases (NIAID). Research at Monash University was also supported by funding provided by the Australian Research Council to the Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics (grant no. CE0562063). --
520 $aABSTRACT.- Type D enterotoxemia, caused by Clostridium perfringens epsilon toxin (ETX), is one of the most economically important clostridial diseases of sheep. Acute type D enterotoxemia is characterized by well-documented lesions in the nervous, cardiocirculatory, and pulmonary systems. However, discrepancies and confusion exist as to whether renal lesions are part of the spectrum of lesions of this condition, which is controversial considering that for many decades it has been colloquially referred to as "pulpy kidney disease". Here, the authors assess renal changes in an experimental model of acute type D enterotoxemia in sheep and evaluate the possible role of ETX in their genesis. Four groups of 6 sheep each were intraduodenally inoculated with either a wild-type virulent C. perfringens type D strain, an etx knockout mutant unable to produce ETX, the etx mutant strain complemented with the wild-type etx gene that regains the ETX toxin production, or sterile culture medium (control group). All sheep were autopsied less than 24 hours after inoculation; none of them developed gross lesions in the kidneys. Ten predefined histologic renal changes were scored in each sheep. The proportion of sheep with microscopic changes and their severity scores did not differ significantly between groups. Mild intratubular medullary hemorrhage was observed in only 2 of the 12 sheep inoculated with the wild-type or etx-complemented bacterial strains, but not in the 12 sheep of the other 2 groups. The authors conclude that no specific gross or histologic renal lesions are observed in sheep with experimental acute type D enterotoxemia. © The Author(s) 2023
653 $aClostridium perfringens type D
653 $aEnterotoxemia
653 $aETX
653 $aExperimental infection
653 $aKidneys
653 $aPLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA
653 $aRenal pathology
653 $aSheep
700 1 $aGARCÍA, J. P.
700 1 $aADAMS, V.
700 1 $aARMENDANO, J.
700 1 $aBEINGESSER, J.
700 1 $aROOD, J.
700 1 $aUZAL, F. A.
773 $tVeterinary Pathology. 2023, vol.60(4):412-419. https://doi.org/10.1177/03009858231171669
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Registro original : |
INIA Las Brujas (LB) |
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Registro completo
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Biblioteca (s) : |
INIA Treinta y Tres. |
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Fecha actual : |
23/01/2023 |
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Actualizado : |
07/03/2023 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
CARRACELAS, G.; GUILPART, N.; CASSMAN, K.G.; GRASSINI, P. |
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Afiliación : |
JULIO GONZALO CARRACELAS GARRIDO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; NICOLÁS GUILPART, University of Nebraska-Lincoln, USA; Université Paris-Saclay, AgroParisTech, INRAE, UMR Agronomie, France.; KENNETH G. CASSMAN, University of Nebraska-Lincoln, USA; PATRICIO GRASSINI, University of Nebraska-Lincoln, USA. |
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Título : |
Distinguishing between yield plateaus and yield ceilings: A case study of rice in Uruguay. |
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Fecha de publicación : |
2023 |
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Fuente / Imprenta : |
Field Crops Research, 2023, volume 292, number 108808. OPEN ACCESS. Doi: https://doi.org/10.1016/j.fcr.2023.108808 |
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Páginas : |
8 p. |
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DOI : |
10.1016/j.fcr.2023.108808 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 3 September 2022; Received in revised form 22 December 2022; Accepted 2 January 2023; Available online 13 January 2023.
Corresponding author. E-mail address: gcarracelas@inia.org.uy (G. Carracelas). |
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Contenido : |
Rice yields in Uruguay have increased rapidly (159 kg-1 ha-1 y-1) between 1990 and 2013. There is evidence, however, of an incipient yield plateau in recent years. The aim of this study was to determine if the recent slowdown in yield gains is because average yield (Ya) has approached the yield potential (Yp) ceiling, which makes it increasingly difficult for farmers to sustain further yield gains. We followed the methodology developed by the Global Yield Gap Atlas to estimate Yp and associated yield gaps for irrigated rice supported by data from high-yield experiments to calibrate the rice simulation model Oryza (v3). Subsequently, the model was used to simulate Yp using long-term daily weather data from seven locations, representing 90 % of total rice area in Uruguay. The exploitable yield gap (Yeg) was calculated as the difference between 80 % of Yp and Ya. Estimated national average Yp was 13.9 Mg ha?1, with relatively small variation across sites, from 13.1 to 15.1 Mg ha-1. Average Ya was 8.3 Mg ha-1, ranging from 7.9 to 8.5 Mg ha-1 across sites, and representing 60 % of Yp. Our analysis suggests there is still room to further increase rice yields in Uruguay, because the Yeg is 2.8 Mg ha-1, which means the current yield plateau is not due to Ya approaching Yp, as has occurred in other high-yield irrigated rice systems in China and California, USA. The approach followed here can help determine whether yield plateaus are occurring due to a small Yeg or other factors. |
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Palabras claves : |
ORYSA SATIVA; RICE; YIELD GAP; YIELD PLATEAU; YIELD POTENTIAL. |
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Asunto categoría : |
F01 Cultivo |
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URL : |
https://www.sciencedirect.com/sdfe/reader/pii/S0378429023000011/pdf
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Marc : |
LEADER 02481naa a2200253 a 4500
001 1063945
005 2023-03-07
008 2023 bl uuuu u00u1 u #d
024 7 $a10.1016/j.fcr.2023.108808$2DOI
100 1 $aCARRACELAS, G.
245 $aDistinguishing between yield plateaus and yield ceilings$bA case study of rice in Uruguay.$h[electronic resource]
260 $c2023
300 $a8 p.
500 $aArticle history: Received 3 September 2022; Received in revised form 22 December 2022; Accepted 2 January 2023; Available online 13 January 2023. Corresponding author. E-mail address: gcarracelas@inia.org.uy (G. Carracelas).
520 $aRice yields in Uruguay have increased rapidly (159 kg-1 ha-1 y-1) between 1990 and 2013. There is evidence, however, of an incipient yield plateau in recent years. The aim of this study was to determine if the recent slowdown in yield gains is because average yield (Ya) has approached the yield potential (Yp) ceiling, which makes it increasingly difficult for farmers to sustain further yield gains. We followed the methodology developed by the Global Yield Gap Atlas to estimate Yp and associated yield gaps for irrigated rice supported by data from high-yield experiments to calibrate the rice simulation model Oryza (v3). Subsequently, the model was used to simulate Yp using long-term daily weather data from seven locations, representing 90 % of total rice area in Uruguay. The exploitable yield gap (Yeg) was calculated as the difference between 80 % of Yp and Ya. Estimated national average Yp was 13.9 Mg ha?1, with relatively small variation across sites, from 13.1 to 15.1 Mg ha-1. Average Ya was 8.3 Mg ha-1, ranging from 7.9 to 8.5 Mg ha-1 across sites, and representing 60 % of Yp. Our analysis suggests there is still room to further increase rice yields in Uruguay, because the Yeg is 2.8 Mg ha-1, which means the current yield plateau is not due to Ya approaching Yp, as has occurred in other high-yield irrigated rice systems in China and California, USA. The approach followed here can help determine whether yield plateaus are occurring due to a small Yeg or other factors.
653 $aORYSA SATIVA
653 $aRICE
653 $aYIELD GAP
653 $aYIELD PLATEAU
653 $aYIELD POTENTIAL
700 1 $aGUILPART, N.
700 1 $aCASSMAN, K.G.
700 1 $aGRASSINI, P.
773 $tField Crops Research, 2023, volume 292, number 108808. OPEN ACCESS. Doi: https://doi.org/10.1016/j.fcr.2023.108808
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